姓名:王珍高
性别:男
出生年月:1990.08
籍贯:湖北恩施
职位:副教授、硕士生导师
二、联系方式
邮箱:zhengao@scau.edu.cn
通讯地址:广州市天河区五山路483号华南农业大学材料与能源学院344室
邮编:510642
三、个人简述
王珍高,博士,副教授,硕士生导师,广东省科协青年科技人才。2020年毕业于华南理工大学,获得材料学博士学位。发表SCI论文40余篇,其中第一/通讯在Nano Lett. (IF 10.8)、Bioact. Mater. (IF 18.9)、Chem. Eng. J. (IF 15.1)、Coord. Chem. Rev. (IF 20.6)、Adv. Healthcare Mater. (IF 10.1)、Carbon (IF 10.9)和ACS Appl. Mater. Interfaces (IF 9.5)等期刊上发表16篇SCI论文。主持了国家自然科学基金青年项目、国家重点研发子课题等项目,相关技术获得中国发明专利授权15项、PCT国际专利3项、美国授权专利1项、新加坡授权专利2项,获得第一届全国博士后创新创业大赛优胜奖、广州市校园高价值专利培育大赛一等奖。主要研究内容如下:(1)光响应特性的抗菌剂设计及其糖尿病难愈合伤口治疗应用:通过原位化学沉积技术构建了一些列等离子共振增强的二维氯氧化铋纳米异质结,通过理论计算和实验数据揭示了纳米异质结光催化抗菌机制,实现了糖尿病难愈合伤口的治疗。(2)用于小分子药物分析的抗菌电极:通过原位电化学沉积技术构建了一些列导电聚合物基抗菌电极,揭示了等离子共振增强的光电催化反应机制,实现了过氧化氢、葡萄糖等小分子的高效检测。(3)仿生多孔骨植入物:构建了的外场响应的三维多孔结构植入物,揭示了水分子与聚合物表界面作用的调控机理,实现了水在纳米结构表面超润滑传输。
四、教育背景
2017.09-2020.12 华南理工大学,材料科学与工程学院,博士
2014.09-2017.04 华南理工大学,材料科学与工程学院,硕士
2010.09-2014.06 湖北大学,材料科学与工程学院,学士
五、工作经历
2023.06-2023.12 香港大学临床医学学院,Honorary Research Associate
2021.01-2024.10 华南理工大学材料科学与工程学院,博士后
六、科研方向
电活性生物材料、生物质材料3D打印
七、科研论著
1. Zhengao Wang, Wei Li, Youzhun Fan, Cairong Xiao, Zhifeng Shi, Yunbing Chang, Guoyan Liang, Chengli Liu, Zurong Zhu, Peng Yu, Xuebin Yang *, Zhiguo Song *, Chengyun Ning *, Localized Surface Plasmon Resonance‐Enhanced Photocatalytic Antibacterial of In‐situ Sprayed 0D/2D Heterojunction Composite Hydrogel for Treating Diabetic Wound, Advanced Healthcare Materials, 2024, 2303836
2. Jialuo Ai1, Yixuan Huang, Zhaoyi Yin, Yingshan Deng, Ling Yan, Jingwen Liao, Guoyan Liang, Chong Chen, Yunbing Chang, Cairong Xiao, Jiale Zhou, Zurong Zhu, Chengli Liu, Zhuo Jiang*, Chengyun Ning*, Zhengao Wang*, Sea Anemone-inspired Conducting Polymer Sensing Platform for Integrated Detection of Tumor Protein Marker and Circulating Tumor Cell, Advanced Healthcare Materials, 2024, 2401305
3. Senwei Liu, Lei Qian, Yucong Wu, Lei Zhou, Xinggang Xu, Jiapeng Yang, Chengli Liu, Zurong Zhu, Jie Shu, Zhengao Wang*, Jinxia Zhai*, Chengyun Ning, Enhanced long-term performance of ureteral stents with functional coating: Combating bacterial adhesion and inhibiting encrustation, Progress in Organic Coatings, 2024, 192, 108512,
4. Chengli Liu, Yuman Li, Wei Li, Youzhun Fan, Wuyi Zhou, Cairong Xiao, Peng Yu, Yueyao Liu, Xiangqian Liu, Zhiguang Huang, Xuebin Yang*, Chengyun Ning*, Zhengao Wang*, LSPR-enhanced photoresponsive antibacterial efficiency of Bi/MoS2-loaded fibrin gel for management of diabetic wounds, International Journal of Biological Macromolecules, 2024, 277, 134430
5. Wang Zhengao, Liu Guangyu, Chen Wei, Zhang Lu, Qi Zheng, Bai Guanghui, Fan Youzhun, Liu Chengli, Xiao Cairong, Li Wei, Chang Yunbing, Liang Guoyan, Zhou Zhengnan *, Yu Peng, Song Zhiguo*, Ning Chengyun, Contribution of Surface Plasmonic Resonance to Enhanced Photocatalytic Antibacterial Performance of Graphene-based Two-dimensional Heterojunction, Chemical Engineering Journal, 2023, 460, 141720.
6. Zurong Zhu, Lu Zhang, Pinan Liu, Chengli Liu, Jialuo Ai, Youzhun Fan, Senwei Liu, Jinxia Zhai, Guanghui Bai*, Chengyun Ning, Zhengao Wang*, MOF-derived multicore-shell Fe3O4@ Fe@ C composite: An ultrastrong electromagnetic wave absorber. Carbon, 2023, 215, 118477.
7. Anning Chen#, Zhengao Wang#, Hailun Chen, Bo Pang, He Cai1, Ziheng Chen, Chengyun Ning*, Dong Ma*, Jie Tang*, Hongzheng Zhang*, Zwitterion Modified Cochlear Implants Resist Postoperative Infection and Inflammation. Materials Today Bio 2023, 23, 100856.
8. Li Ziyu#, Zhang Jiaqi#, Huang Yixuan, Zhai Jinxia, Liao Guangfu*, Wang Zhengao*, Ning Chengyun*, Development of Electroactive Materials-Based Immunosensor Towards Early-Stage Cancer Detection. Coordination Chemistry Reviews 2022, 471, 214723.
9. Li Wei, Fan Youzhun, Lin Jian, Yu Peng*, Wang Zhengao*, Ning Chengyun*, Near‐Infrared Light-Activatable Bismuth‐Based Nanomaterials for Antibacterial and Antitumor Treatment. Advanced Therapeutics 2022, 2200027.
10. Li Changhao, Xiao Cairong, Zhan Lizhen, Zhang Zhekun, Xing Jun, Zhai Jinxia, Zhou Zhengnan, Tan Guoxin, Piao Jinhua, Zhou Yahong, Qi Suijian*, Wang Zhengao*, Yu Peng*, Ning Chengyun*, Wireless Electrical Stimulation at the Nanoscale Interface Induces Tumor Vascular Normalization. Bioactive Materials 2022, 18, 399-408.
11. Huang Yixuan, Fu Rumin, Zhu Zurong, Liu Chengli, Liu Senwei, Yu Peng, Yan Ling, Zhou Zhengnan*, Ning Chengyun*, Wang Zhengao*, Plasmon-Enhanced Electrocatalysis of Conductive Polymer-Based Nano-Heterojunction for Small Molecule Metabolites Diagnostics. ACS Applied Materials & Interfaces, 2022, 14, 39799.
12. Fan Youzhun#, Wang Zhengao#, Ren Weizhou, Liu Guangyu, Xing Jun, Xiao Taizhong, Li Wei, Li Yongjin*, Yu Peng*, Ning Chengyun, Zhiguo Song*, Space-Confined Synthesis of Thin Polypyrrole Nanosheets in Layered Bismuth Oxychloride for a Photoresponse Antibacterial within the near-Infrared Window and Accelerated Wound Healing. ACS Applied Materials & Interfaces 2022, 14 (32), 36966.
13. Yu Peng, Tan Guoxin, Deng Xuliang, Wang Zhengao*, Ning Chengyun*, Ding Liming*, The Innovation of Biomaterials: From Bioactive to Bioelectroactive. Science China Materials 2022, 1-4.
14. Wang Zhengao#, Yu Peng#, Zhou Jiajia, Liao Jingwen, Zhou Lei, Ran Heying, Zhai Jingxia, Xing Jun, Tan Guoxin, Zhou Zhengnan, Yangfan Li, Chengyun Ning*, and Yahong Zhou*, Ultrafast and on-Demand Oil/Water Separation Membrane System Based on Conducting Polymer Nanotip Arrays. Nano Letters 2020, 20 (7), 4895-4900.
15. Wang Zhengao, Zeng Jinquan, Tan Guoxin, Liao Jingwen, Zhou Lei, Chen Junqi, Yu Peng*, Wang Qiyou, Ning Chengyun*, Incorporating Catechol into Electroactive Polypyrrole Nanowires on Titanium to Promote Hydroxyapatite Formation. Bioactive Materials 2018, 3 (1), 74-79.
16. Wang Zhengao, Zhou Lei, Yu Peng, Liu Yan, Chen Junqi, Liao Jingwen, Li Weiping, Chen Wei, Zhou Wenhao, Yi Xin, Ouyang Kongyou, Zhou Zhengnan, Tan Guoxin, Ning Chengyun*, Polydopamine‐Assisted Electrochemical Fabrication of Polypyrrole Nanofibers on Bone Implants to Improve Bioactivity. Macromolecular Materials and Engineering 2016, 301 (11), 1288-1294.
八、授权发明专利
国际专利
1. Chengyun Ning, Zhengao Wang, Peng Yu, Shiqian Hu, Tiantian Yao, Wen Luo, Guoxin Tan. Nanocone Structure Composite Material for Capturing Cancer Cells, Preparation Method Therefor and Use Thereof. 国际申请号:PCT/CN2017/112178, 美国专利申请号:US 2020/0191780A1, 新加坡授权号:11201910803T.
2. Chengyun Ning, Zhengao Wang, Peng Yu, Lei Qian, Zhengnan Zhou, Junqi Chen, Lei Zhou, Guoxin Tan. Glucose Sensor Electrode, Preparation Method Therefor And Use Thereof. 国际申请号:PCT/CN2018/106842, 美国专利申请号US 2021/0215632A1, 新加坡专利授权号11202007810V.
3. Chengyun Ning, Peng Yu, Zhengao Wang, Zhengnan Zhou, Canghao Li, Kejia Zhang. Bone Implantation Material with Micro-region Potential Difference and Preparation Method Therefor. 国际申请号:PCT/CN2018/111947.
中国授权发明专利
1. 宁成云,王珍高,黄怡萱,李潇,陈宇航,于鹏,李玮,周蕾,李扬帆,杨虹. 一种导电聚吡咯/中药复合水凝胶及其制备方法与应用. 授权号:CN112353754B,2022-06-14.
2. 宁成云,王珍高,于鹏,谭帼馨,胡诗迁,姚甜甜,罗雯. 一种用于捕获癌细胞的纳米锥结构复合材料及其制备方法与应用. 授权号:CN107177553B,2021-05-25.
3. 宁成云,王珍高,于鹏,钱磊,周正难,邢君,陈俊琪,周蕾,谭帼馨. 一种葡萄糖传感器电极及其制备方法与应用. 授权号:CN108663426B,2020-09-22.
4. 宁成云,王珍高,翟锦霞,于鹏. 一种导电聚吡咯/聚多巴胺纳米纤维及其制备方法与应用. 授权号:CN106474546B,2019-10-18.
5. 宁成云,于鹏,王珍高,周正难,黎昌昊,张珂嘉. 一种微区电势差异性骨植入材料及其制备方法. 授权号:CN108744053B,2020-09-22.
6. 于鹏,黄怡萱,宁成云,王珍高,刘广宇,李玮,周蕾,范磊,张珂嘉,冉合迎. 一种纳米锥结构聚吡咯/金属网多孔过滤膜及其制备方法与应用. 授权号:CN111530305B,2021-07-20.
7. 宁成云,冉合迎,于鹏,王珍高,李扬帆,周正难,翟锦霞,杨法邦. 一种具有免疫响应的电活性钛植入体及其制备方法. 授权号:CN113198043B,2022-04-22.
8. 宁成云,姚甜甜,陈俊祺,王珍高,张珂嘉,胡诗迁. 一种压电抗肿瘤材料及其制备方法与应用. 授权号:CN109704809B,2022-01-18.
9. 宁成云,姚甜甜,陈俊祺,肖才榕,王珍高,张珂嘉,胡诗迁. 一种高效促成骨铌酸钾钠基压电植入材料及其制备方法与应用. 授权号:CN109574664B,2021-09-21.
10. 宁成云,胡诗迁,周蕾,陈俊祺,姚甜甜,王珍高,于鹏. 一种多巴胺介导的聚吡咯导电水凝胶及其制备方法. 授权号:CN109575318B,2021-09-21.
11. 宁成云,付如民,周蕾,于鹏,王珍高. 一种具有电活性的高强度水凝胶及其制备方法和应用. 授权号:CN109106980B,2021-07-20.
12. 宁成云,姚甜甜,陈俊祺,肖才榕,王珍高,张珂嘉,胡诗迁. 一种高效抗肿瘤铌酸钾钠基压电材料及其制备方法与应用. 授权号:CN109485418B,2021-07-20.
13. 宁成云,李玮,王珍高,于鹏,张哲琨,张欢,杨法邦. 一种近红外响应Bi/BiOCl异质结复合纤维蛋白凝胶及其制备与应用. 授权号:CN114748450B, 2023-08-22.
14. 宁成云,黄怡萱,王珍高,于鹏,刘城利,李梓毓,李明睿,张珈绮,颜嘉琪. 一种导电聚合物生物传感器电极材料及其制备方法与应用. 授权号:CN114369241B, 2023-01-24.
15. 宁成云,黄晓,于鹏,李扬帆,邢君,周正难,王珍高,冉合迎,刘广宇,钟新香. 一种表面具有异质结抗菌膜层的钛植入体及其制备方法与应用. 授权号:CN113106448B, 2022-11-18.
九、科研项目
1. 国家自然科学基金青年基金:钛植入体表面电学微环境的构建及其与单细胞作用机制研究,30万元,主持;
2. 国家重点研发计划:高品质医用金属粉体材料及增材制造金属植入体研发,子课题负责人;承担经费75万元;
3. 广东省科协青年科技人才培育计划:3D打印压电仿生支架智能调控成骨和抗骨肉瘤细胞的作用机制,3万元,主持;
4. 中央高校基本科研业务费面上项目:骨修复材料表面力-电耦合微环境调控单细胞行为的机制研究,10万元,主持;
十、写给学生的话
培养天马行空的创造力,锻造脚踏实地的执行力;拥抱人工智能时代,开拓生物材料的边界。